Le Charpentier Y, Auriol M
Service central d'anatomie et cytologie pathologiques, Groupe hospitalier Pitié-Salpêtrière, Paris.
Rev Stomatol Chir Maxillofac. 1994;95(4):306-9.
Histological study is made on labial salivary gland biopsies in three usual circumstances: presence of a sicca syndrome; suspicion of a Gougerot-Sjogren's disease or of another systemic disease (sarcoïdosis; amyloïdosis). Its aim is: to appreciate the accuracy of the biopsy; to analyse elementary lesions and to suggest an etiologic diagnosis. The authors put emphasis on the interest: 1) to use new techniques of immunocytochemistry or molecular biology to appreciate the degree of evolutivity of lesions; 2) to quantify lymphoïd infiltrates, fibrosis and epithelial alterations; 3) to formulate results with regard not only to the etiological Diagnosis but also to the glandular Destruction by means of a double descriptive score: the "D.D." score.
对唇唾液腺活检进行组织学研究，研究通常在以下三种情况下进行：存在干燥综合征；怀疑患有古热-舍格伦病或其他全身性疾病（结节病、淀粉样变性）。其目的是：评估活检的准确性；分析基本病变并提出病因诊断。作者强调了以下几点的重要性：1）使用免疫细胞化学或分子生物学的新技术来评估病变的进展程度；2）对淋巴细胞浸润、纤维化和上皮改变进行量化；3）不仅根据病因诊断，还通过双重描述性评分“D.D.”评分来阐述腺体破坏情况。
