Gerdts E, Stangeland L, Engedal H, Nordrehaug J E
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Scand J Thorac Cardiovasc Surg. 1994;28(1):25-9. doi: 10.3109/14017439409098706.
Doppler echocardiography was performed on 108 patients 4-15 days after implantation of a Medtronic-Hall, Biocor or Carpentier-Edwards S.A.V. prosthetic aortic valve because of aortic stenosis. Significant correlation was found between the in vitro (maker-declared) and the Doppler-estimated effective prosthetic valve orifice area (r = 0.70, p < 0.01). Doppler-estimated prosthetic valve orifice area, but not transprosthetic blood velocities, discriminated between different sizes of Medtronic-Hall and Biocor valves. The effective orifice area in these valves was 57% of the in vitro area, but in Carpentier-Edwards valves it was only 43%. Transprosthetic blood velocity was inversely related to orifice area in men, but not in women, who also had longer duration of systole and better preservation of systolic left ventricular function. The data suggest that the effective prosthetic valve areas found in patients are significantly smaller than the experimental in vitro areas. Prosthesis size and type, anatomic and hemodynamic variables and gender are important in Doppler estimation of effective valve area.
因主动脉狭窄，对108例植入美敦力 - 霍尔、百生康或卡朋蒂埃 - 爱德华兹S.A.V.人工主动脉瓣膜的患者在植入后4至15天进行了多普勒超声心动图检查。发现体外（制造商声明）与多普勒估计的人工瓣膜有效瓣口面积之间存在显著相关性（r = 0.70，p < 0.01）。多普勒估计的人工瓣膜瓣口面积而非跨瓣血流速度可区分不同尺寸的美敦力 - 霍尔和百生康瓣膜。这些瓣膜的有效瓣口面积为体外面积的57%，但卡朋蒂埃 - 爱德华兹瓣膜仅为43%。跨瓣血流速度在男性中与瓣口面积呈负相关，但在女性中并非如此，女性的收缩期持续时间更长且左心室收缩功能保存更好。数据表明，患者中发现的人工瓣膜有效面积明显小于实验体外面积。假体尺寸和类型、解剖和血流动力学变量以及性别在多普勒估计有效瓣膜面积方面很重要。
