一种简便快速的抑制素生物测定法。
A convenient and rapid bioassay for inhibin.
作者信息
Chari S, Duraiswami S, Franchimont P
出版信息
Horm Res. 1976;7(3):129-37. doi: 10.1159/000178720.
PMID:793975
Abstract
A bioassay for inhibin, based on a dose-dependent suppression of HCG-induced ovarian weight increase in intact, immature female rats, is described. The method is specific and has acceptable sensitivity and precision such that it lends itself to statistically valid quantitative assay of inhibin activity. Being a 24-hour assay, it is conveniently and rapid performed as well as being a multiple bioassay for estimating potencies of various preparations.
摘要
本文描述了一种基于抑制素对完整未成熟雌性大鼠中由人绒毛膜促性腺激素（HCG）诱导的卵巢重量增加呈剂量依赖性抑制作用的生物测定法。该方法具有特异性，灵敏度和精密度均可接受，因此适用于对抑制素活性进行具有统计学意义的定量测定。作为一种24小时测定法，它操作方便、快速，并且是一种用于评估各种制剂效力的多重生物测定法。
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