Goh K L, Parasakthi N, Peh S C, Puthucheary S D, Wong N W
Department of Medicine, University Hospital, University of Malaya, Kuala Lumpur, Malaysia.
Singapore Med J. 1994 Apr;35(2):161-2.
With the increasing recognition of the importance of H. pylori in gastrointestinal disease, there is a need for a reliable, efficient and yet inexpensive diagnostic test. The performance of the rapid urease test (RUT) as an endoscopy suite diagnostic test was compared to the established methods of culture, histology and Gram stain of tissue smear, in 274 gastric biopsy samples. Histology had the highest sensitivity of 99.3% followed by the RUT (96.6%). Culture and Gram stain of tissue smear had 100% specificity, while the rapid urease test had 99.2% specificity. The RUT had a positive predictive value of 99.3% and a negative predictive value of 96.2%. The RUT is an inexpensive, rapid and reliable diagnostic test of H. pylori infection.
随着人们越来越认识到幽门螺杆菌在胃肠道疾病中的重要性，需要一种可靠、高效且廉价的诊断测试。在274份胃活检样本中，将快速尿素酶试验（RUT）作为内镜室诊断测试的性能与既定的培养、组织学和组织涂片革兰氏染色方法进行了比较。组织学的敏感性最高，为99.3%，其次是RUT（96.6%）。组织涂片的培养和革兰氏染色特异性为100%，而快速尿素酶试验的特异性为99.2%。RUT的阳性预测值为99.3%，阴性预测值为96.2%。RUT是一种廉价、快速且可靠的幽门螺杆菌感染诊断测试。
