Frazier O H, Macris M P
Department of Surgery, University of Texas Medical School at Houston.
Surg Clin North Am. 1994 Oct;74(5):1169-82.
This article summarizes general practices in cardiac transplantation, including the selection of recipients and pretransplant management, selection of donors, surgical technique, management of perioperative complications, and induction and maintenance protocols for immunosuppression. Advancements in the management of rejection and infection also are included. Coronary artery disease is the most frequent cause of late death in spite of improved immunosuppressive regimens, antiplatelet agents, and lipid-controlling drugs. Still, long-term survival has improved markedly. A brief description of the Texas Heart Institute experience with 532 cardiac transplants is provided.
本文总结了心脏移植的一般做法，包括受者的选择和移植前管理、供者的选择、手术技术、围手术期并发症的处理以及免疫抑制的诱导和维持方案。还包括排斥反应和感染管理方面的进展。尽管免疫抑制方案、抗血小板药物和降脂药物有所改进，但冠状动脉疾病仍是晚期死亡的最常见原因。不过，长期生存率已显著提高。本文还简要介绍了德克萨斯心脏研究所532例心脏移植的经验。
