Hernandez L E, Connelly P J, Strickler S A, Akers M M, Dunn M M
Wright State University, Department of Surgery, Miami Valley Hospital, Dayton, OH 45409.
Surgery. 1994 Oct;116(4):610-4; discussion 614-5.
Stereotaxic core breast biopsy (SCBB) has been proposed as a cost-effective and reliable method of evaluating mammographic lesions. This study evaluates an initial experience with SCBB and assesses the adequacy of the biopsy specimens obtained.
Two hundred forty-one SCBB were performed on 221 patients during 13 months by four radiologists. Mammograms were assigned a suspicion index on a scale of 1 to 5. One pathologist performed a blinded retrospective review of all SCBB specimens and assigned an adequacy score based on the quality and amount of the tissue present.
The majority of SCBB were ordered by general surgeons (67%). A suspicion index score of 3 was assigned to 74% of lesion specimens. Twelve percent of specimens were malignant. Overall SCBB adequacy (score > or = 2) was 77%. Adequacy was present in 74% of benign biopsy specimens as compared with 100% of malignant specimens (p < 0.005). Only 62% of specimens reported as benign without specific features were adequate. There were no differences in adequacy between individual radiologists or during the study period.
SCBB is largely used by surgeons to assess indeterminate mammographic lesions. One of four benign specimens was inadequate. Benign SCBB specimens must be interpreted with caution.
立体定向乳腺核心活检（SCBB）已被提议作为一种评估乳腺钼靶病变的经济有效且可靠的方法。本研究评估了SCBB的初步经验，并评估了所获取活检标本的充足性。
在13个月期间，由四位放射科医生对221例患者进行了241次SCBB。乳腺钼靶检查被赋予1至5级的可疑指数。一位病理学家对所有SCBB标本进行了盲法回顾性审查，并根据所存在组织的质量和数量给出充足性评分。
大多数SCBB是由普通外科医生要求进行的（67%）。74%的病变标本可疑指数评分为3。12%的标本为恶性。总体SCBB充足率（评分≥2）为77%。良性活检标本的充足率为74%，而恶性标本为100%（p<0.005）。报告为无特定特征的良性标本中只有62%是充足的。不同放射科医生之间或研究期间的充足率没有差异。
SCBB主要由外科医生用于评估不确定的乳腺钼靶病变。四分之一的良性标本不充足。对良性SCBB标本的解读必须谨慎。
