Samko A N, Savchenko A P, Chazova I E, Lazutkina V K, Mareev V Iu, Belenkov Iu N
Ter Arkh. 1994;66(5):62-6.
To ascertain the role of invasive investigations in the diagnosis of primary pulmonary hypertension (PPH), 12 PPH patients underwent catheterization of the left and right heart compartments, contrast right and left ventriculography and oximetry. Compared to control values, the patients had high pressure in the pulmonary artery and right ventricle. Some of them exhibited elevated pressure in the right atrium. Pulmonary artery wedge pressure, left ventricular end-diastolic and systolic, diastolic pressure in the aorta did not differ significantly from those in the controls. Right and left ventriculography revealed an increase in the end-systolic and end-diastolic volumes of the right ventricle which diminished its stroke index and ejection fraction. The latter two were reduced in the left ventricle also. Because the procedure was well tolerated by the patients, it is recommended for PPH diagnosis and follow-up.
为确定侵入性检查在原发性肺动脉高压（PPH）诊断中的作用，12例PPH患者接受了左右心腔导管检查、左右心室造影及血氧测定。与对照值相比，患者肺动脉和右心室压力较高。部分患者右心房压力升高。肺动脉楔压、左心室舒张末期和收缩期压力以及主动脉舒张压与对照组无显著差异。左右心室造影显示右心室收缩末期和舒张末期容积增加，导致其每搏指数和射血分数降低。左心室的这两项指标也降低。由于患者对该检查耐受性良好，故推荐用于PPH的诊断和随访。
