Kozlovskaia L V, Tareeva I E, Mukhin N A, Neverov N I, Karryeva B Ch
Ter Arkh. 1994;66(6):11-4.
Boyden camera tests, chemiluminescence of urinary supernatant, passive hemagglutination tests were used in measuring chemotactic properties of the urine, intensity of free-radical processes, fibronectin urine concentrations, respectively, in 31 glomerulonephritis (GN) patients. The above parameters were closely related to nephritis activity. These were much lower in patients with nephritis remission, than in subjects with nephrotic syndrome or exacerbation of latent nephritis. Chemotactic activity and intensity of free-radical processes were unrelated to protein urea which, however, correlated with fibronectin concentrations (r = 0.35, p < 0.05). The authors discuss the role of the mediators' values in evaluation of local renal inflammation and feasibility of their use as criteria of nephritis activity and prognosis.
对31例肾小球肾炎（GN）患者分别采用博伊登小室试验、尿上清液化学发光法、被动血凝试验来测定尿液的趋化特性、自由基过程强度、尿纤连蛋白浓度。上述参数与肾炎活动密切相关。与肾病综合征患者或隐匿性肾炎加重患者相比，肾炎缓解期患者的这些参数要低得多。趋化活性和自由基过程强度与蛋白尿无关，然而，蛋白尿与纤连蛋白浓度相关（r = 0.35，p < 0.05）。作者讨论了这些介质值在评估局部肾脏炎症中的作用以及将其用作肾炎活动和预后标准的可行性。
