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术后内脏低血压是心脏手术后胃肠道并发症的常见原因。

Postoperative visceral hypotension the common cause for gastrointestinal complications after cardiac surgery.

作者信息

Christenson J T, Schmuziger M, Maurice J, Simonet F, Velebit V

机构信息

Cardiovascular Unit Hôpital de la Tour, Meyrin-Geneva, Switzerland.

出版信息

Thorac Cardiovasc Surg. 1994 Jun;42(3):152-7. doi: 10.1055/s-2007-1016478.

Abstract

In order to identify peroperative risk factors and to evaluate different etiological factors in developing postoperative gastrointestinal complications, clinical variables were studied in 3493 patients undergoing adult cardiac surgery. There were 86 gastrointestinal complications, 2.9%, with an overall morality among these of 22.1%: the mortality rate was 3.9% for all patients undergoing cardiac surgery at our institution (p < 0.001). Paralytic ileus, intestinal ischemia, and acute cholecystitis were the most frequently seen complications. Arterial hypertension, smoking and poor preoperative cardiac function, clinical instability, and the need for an emergency operation were distinct clinical risk factors. Cardiopulmonary bypass time was, by itself, not an important factor. Embolic etiology was also ruled out. The incidence of peroperative myocardial infarction, low postoperative cardiac output necessitating massive use of vasopressor substances and/or intraaortic balloon pumping were significantly more often observed in patients who subsequently developed gastrointestinal complications. The common etiological factor in developing gastrointestinal complications of any kind, after cardiac surgery, seems to be postoperative splanchnic hypoperfusion with visceral ischemia. In order to reduce postoperative morbidity and mortality it is essential to identify patients at risk, support preoperative poor cardiac function, and to carefully monitor these patients postoperatively for abdominal complications to reach an early diagnosis.

摘要

为了确定围手术期风险因素并评估术后胃肠道并发症发生的不同病因,我们对3493例接受成人心脏手术的患者的临床变量进行了研究。共有86例胃肠道并发症,发生率为2.9%,这些患者的总体死亡率为22.1%:在我们机构接受心脏手术的所有患者的死亡率为3.9%(p < 0.001)。麻痹性肠梗阻、肠缺血和急性胆囊炎是最常见的并发症。动脉高血压、吸烟、术前心功能差、临床不稳定以及需要急诊手术是明显的临床风险因素。体外循环时间本身并不是一个重要因素。栓塞病因也被排除。围手术期心肌梗死的发生率、术后因低心输出量而需要大量使用血管活性药物和/或主动脉内球囊反搏在随后发生胃肠道并发症的患者中明显更常见。心脏手术后发生任何类型胃肠道并发症的常见病因似乎是术后内脏低灌注伴内脏缺血。为了降低术后发病率和死亡率,识别高危患者、改善术前较差的心功能并在术后仔细监测这些患者的腹部并发症以实现早期诊断至关重要。

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