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[豚鼠肝脏中红细胞生成的产前动态]

[The prenatal dynamics of erythropoiesis in the liver of the guinea pig].

作者信息

Nikonenko A G

出版信息

Tsitol Genet. 1994 Mar-Apr;28(2):7-10.

PMID:7941018
Abstract

Erythroid cell kinetics in the liver of guinea pig embryo was investigated on the semithin epon sections with stereologic and morphometrical methods. It was shown that from 20 to 60 days of prenatal development the volume density (VD) of proerythroblasts decreased 15 times. A decrease in the VD of another erythroblasts was less pronounced. These changes coincided with the liver parenchyma reconstruction. It was concluded that the main influence on erythroid cell kinetics was determined by a surpassing disappearance of the precursor cells from the prenatal liver and, also, that stability of some morphological parameters of hemopoietic stroma was important for realization of the liver hemopoietic activity.

摘要

采用体视学和形态计量学方法,在半薄环氧树脂切片上研究了豚鼠胚胎肝脏中红细胞系细胞动力学。结果表明,在产前发育的20至60天期间,早幼红细胞的体积密度(VD)下降了15倍。其他红细胞的VD下降则不太明显。这些变化与肝实质重建相吻合。得出的结论是,对红细胞系细胞动力学的主要影响是由产前肝脏中前体细胞的过度消失决定的,此外,造血基质某些形态学参数的稳定性对肝脏造血活性的实现也很重要。

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