Filiptsev P Ia, Ratobyl'skiĭ G V, Suslov V P, Ivanov I A, Loseva T V
Urol Nefrol (Mosk). 1993 Jan-Feb(1):37-42.
To define the criteria for a differential approach to operative treatment of uremic osteodystrophy arising in hemodialysis 51 patients were examined clinically, biochemically and roentgenologically before and after parathyroidectomy. Basing on the X-ray picture, the patients were divided into 3 groups: patients with fibrous osteodystrophy seen at X-ray examination (group 1); patients with fibrous osteodystrophy, osteomalacia in predominance of secondary hyperthyroidism (group 2); patients with osteodystrophy and osteomalacia in predominance of osteomalacia syndrome (group 3); patients with uremic osteodystrophy diagnosed only biochemically. Parathyroidectomy proved most effective in group 1 patients. For group 2 patients it is indicated in a subtotal or partial form in a failure of the conservative treatment. In group 3 patients parathyroidectomy is not recommended to avoid a drastic progress of osteomalacia.
为了确定针对血液透析患者出现的尿毒症骨营养不良进行手术治疗的鉴别方法标准,对51例患者在甲状旁腺切除术前和术后进行了临床、生化及X线检查。根据X线表现,将患者分为3组:X线检查显示纤维性骨营养不良的患者(第1组);以继发性甲状腺功能亢进为主的纤维性骨营养不良、骨软化症患者(第2组);以骨软化症综合征为主的骨营养不良和骨软化症患者(第3组);仅通过生化检查诊断为尿毒症骨营养不良的患者。甲状旁腺切除术对第1组患者最为有效。对于第2组患者,在保守治疗无效时建议进行次全或部分切除。对于第3组患者,不建议进行甲状旁腺切除术,以免骨软化症急剧进展。