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[根据大鼠获得主动回避条件反射能力选择的不同焦虑水平]

[Different anxiety levels in rats selected for their ability to acquire the conditioned reflex of active avoidance].

作者信息

Zhukov D A, Vinogradova E P

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 May-Jun;44(3):591-6.

PMID:7941723
Abstract

Experiments were carried out in rat strains selected for high (KHA) and low (KLA) rates of active avoidance conditioning in a shuttle box. The elevated plus-maze was used for anxiety measurements. Naive KHA rats, as compared with KLA ones, demonstrated much higher anxiety scores. Inescapable electric footshock had opposite effects on anxiety levels in KHA and KLA rats, i.e., it increased anxiety scores in KLA rats and decreased in KHA. The results point to the role of anxiety in adaptive behaviour, e.g., in learning abilities.

摘要

在穿梭箱中对主动回避条件反射率高(KHA)和低(KLA)的大鼠品系进行了实验。高架十字迷宫用于测量焦虑水平。与KLA大鼠相比,未经过训练的KHA大鼠表现出更高的焦虑评分。不可逃避的足部电击对KHA和KLA大鼠的焦虑水平有相反的影响,即它增加了KLA大鼠的焦虑评分,而降低了KHA大鼠的焦虑评分。结果表明焦虑在适应性行为(如学习能力)中起作用。

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