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[情绪应激对因主动回避能力不同而被挑选出的大鼠行为和内分泌指标的影响]

[The effect of emotional stress on the behavioral and endocrine indices of rats selected for their contrasting capacities for active avoidance].

作者信息

Galeeva A Iu, Zhukov D A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1996 Sep-Oct;46(5):929-36.

PMID:9054145
Abstract

Female rats of two strains selected for high (Koltushi high avoidance, KHA) and low (Koltushi low avoidance, KLA) acquisition of active avoidance of shock in a two-way shuttle-box were exposed to emotional stress accompanied by pain and without it. Emotional stress with pain (electrical paw stimulation) had no effects on behavioural and endocrine responses. It was found out that behaviour of KHA rats with their active behavioural strategy was not affected by the emotional stress without pain. In contrast, KLA rats demonstrated enhanced locomotion and exploratory activity, decreased grooming and anxiety. There were no changes in endocrine stress responses. Our findings suggest putative beneficial effect of emotional stress on the animals with passive behavioural strategy.

摘要

选用两种品系的雌性大鼠,一种是在双向穿梭箱中主动逃避电击能力强的(科尔图希高回避,KHA),另一种是主动逃避电击能力弱的(科尔图希低回避,KLA),使其分别暴露于伴有疼痛和不伴有疼痛的情绪应激中。伴有疼痛的情绪应激(电刺激爪部)对行为和内分泌反应没有影响。结果发现,具有主动行为策略的KHA大鼠的行为不受无疼痛情绪应激的影响。相比之下,KLA大鼠表现出运动和探索活动增强,梳理行为和焦虑减少。内分泌应激反应没有变化。我们的研究结果表明,情绪应激对具有被动行为策略的动物可能具有有益作用。

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