Osca García J M, Morera Martínez J F, Catalá Barceló T, Alfonso Gil R, Ruiz Cerdá J L, Martínez Jabaloyas J M, Jiménez Cruz J F
Servicio de Urología, Hospital La Fe, Valencia.
Actas Urol Esp. 1994 Jun;18(6):646-50.
An evaluation was made on the risk of having a second primary neoplasia following vesical tumor diagnosis. All patients attended the 'Hospital La Fe' and had been diagnosed between 1984 and 1993. A total of 238 vesical tumours were studied, 45 (15.9%) with associated second neoplasia; in 34 cases the vesical tumour was the first one to be diagnosed. The number of tumors seen was compared to expected figures, according to the appropriate incidence rates by age, sex and tumour type, taken out from the Spanish section of the 1987 edition of "Cancer Incidence in Five Continents". An increase over the expected values of second neoplasias for lung, prostate, kidney and bone cancer was found. Sixty percent developed concurrently (within 6 months from initial diagnosis). Most vesical tumours were infiltrant, thus conditioning both the prognosis and the second neoplasia. The likely factors implied in this phenomenon are discussed.
对膀胱肿瘤诊断后发生第二原发性肿瘤的风险进行了评估。所有患者均在“拉费医院”就诊，诊断时间为1984年至1993年。共研究了238例膀胱肿瘤，其中45例（15.9%）伴有第二原发性肿瘤；34例中膀胱肿瘤是首个被诊断出的肿瘤。根据1987年版《五大洲癌症发病率》西班牙部分按年龄、性别和肿瘤类型的适当发病率，将观察到的肿瘤数量与预期数字进行了比较。发现肺癌、前列腺癌、肾癌和骨癌的第二原发性肿瘤数量高于预期值。60%的第二原发性肿瘤在初诊后6个月内同时发生。大多数膀胱肿瘤为浸润性，因此影响预后和第二原发性肿瘤。讨论了这一现象中可能涉及的因素。
