Brouland J P, Meeus F, Rossert J, Hernigou A, Gentric D, Jacquot C, Diebold J, Nochy D
Unité INSERM U 28, Département de Néphrologie, Hôpital Broussais, Paris, France.
Am J Kidney Dis. 1994 Oct;24(4):586-9. doi: 10.1016/s0272-6386(12)80217-4.
Renal lymphoma is commonly secondary to lymphomatous infiltration of the kidneys in disseminated lymphoma and advanced stage IV disease. We describe a 57-year-old white woman presenting with an acute renal failure due to a bilateral "primary" B-cell lymphoma infiltration of the kidneys. The diagnosis of the lymphoma was made by renal biopsy. The striking feature observed was a destructive infiltration of the kidney by a malignant B-cell lymphoma that left the renal capsule intact, without any sign of secondary localization on the hilar regions. Physical examination did not reveal any peripheral lymphadenopathy or hepatosplenomegaly. A bilateral infiltration of both kidneys was the only feature shown by computed tomography and renal angiography. This case raises the question of the occurrence of a primary B-cell lymphoma in a nonlymphoid organ, which was diagnosed by renal biopsy at a time when the development was exclusively renal in origin.
肾淋巴瘤通常继发于播散性淋巴瘤和晚期IV期疾病时肾脏的淋巴瘤浸润。我们报告一例57岁白人女性，因双侧“原发性”B细胞淋巴瘤浸润肾脏导致急性肾衰竭。淋巴瘤的诊断通过肾活检确定。观察到的显著特征是恶性B细胞淋巴瘤对肾脏的破坏性浸润，肾包膜完整，肾门区域无任何继发性定位迹象。体格检查未发现任何外周淋巴结肿大或肝脾肿大。计算机断层扫描和肾血管造影仅显示双侧肾脏浸润。该病例提出了非淋巴器官中发生原发性B细胞淋巴瘤的问题，在疾病仅起源于肾脏时通过肾活检确诊。
