Smythe M, Loughlin K, Schad R F, Lucarroti R L
Department of Pharmaceutical Services, William Beaumont Hospital, Royal Oak, MI 48072.
Am J Hosp Pharm. 1994 Jun 1;51(11):1433-40.
The pharmacy and nursing time requirements, quality of postoperative pain control, and cost of patient-controlled analgesia (PCA) and intramuscular (i.m.) analgesic therapy were studied. All timings were conducted with a stopwatch on a single nursing unit that primarily receives gynecologic surgery patients. The various work elements involved in each type of therapy were timed individually. Both quality of analgesia and cost were evaluated in a prospective, randomized study in hysterectomy patients. I.M. patients received meperidine hydrochloride 75-100 mg every three to four hours as needed. PCA patients had access to morphine sulfate 1 mg or meperidine hydrochloride 10 mg, with a six-minute lockout period. The patients scored their pain every four hours. Direct costs for PCA were calculated as drug cost plus tubing cost plus form cost plus maintenance cost plus depreciation cost. Direct costs for i.m. therapy consisted of the cost of drugs. The total mean nursing time per patient was 16.9 minutes for PCA and 10.7 minutes for i.m. therapy. Pharmacy time per patient was 5.1 minutes longer for PCA than for i.m. therapy. Thirty-six hysterectomy patients (17 i.m. and 19 PCA) were enrolled in the study of pain control and cost. Among i.m. patients, 64% of the pain scores were mild or worse, compared with 40% for PCA patients. The median pain scores were moderate for i.m. patients and mild for PCA patients. Scores tended to be lower for PCA patients at 16 and 20 hours. Although equal numbers of patients in the two groups experienced nausea, i.m. patients needed more doses of antiemetics than PCA patients.(ABSTRACT TRUNCATED AT 250 WORDS)
对患者自控镇痛(PCA)和肌内注射(i.m.)镇痛疗法的药房和护理时间要求、术后疼痛控制质量以及成本进行了研究。所有计时均在主要接收妇科手术患者的单一护理单元使用秒表进行。对每种治疗方式涉及的不同工作环节分别计时。在一项针对子宫切除术患者的前瞻性随机研究中评估了镇痛质量和成本。肌内注射患者根据需要每三到四小时接受75 - 100毫克盐酸哌替啶。PCA患者可使用1毫克硫酸吗啡或10毫克盐酸哌替啶,锁定时间为6分钟。患者每四小时对疼痛进行评分一次. PCA的直接成本计算为药物成本加输液管成本加表格成本加维护成本加折旧成本。肌内注射疗法的直接成本包括药物成本。PCA每位患者的总平均护理时间为16.9分钟,肌内注射疗法为10.7分钟。PCA每位患者的药房时间比肌内注射疗法长5.1分钟。三十六名子宫切除术患者(17名肌内注射和19名PCA)参与疼痛控制和成本研究. 在肌内注射患者中,64%的疼痛评分处于轻度或更差水平,而PCA患者为40%。肌内注射患者的疼痛评分中位数为中度,PCA患者为轻度。PCA患者在16小时和20小时时的评分往往较低。尽管两组中经历恶心的患者数量相同,但肌内注射患者比PCA患者需要更多剂量的止吐药。(摘要截选至250字)