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肥胖、妊娠与妊娠晚期左心室功能

Obesity, pregnancy, and left ventricular functioning during the third trimester.

作者信息

Veille J C, Hanson R

机构信息

Department of Obstetrics and Gynecology, Bowman Gray School of Medicine, Winston-Salem, NC 27157-1066.

出版信息

Am J Obstet Gynecol. 1994 Oct;171(4):980-3. doi: 10.1016/0002-9378(94)90018-3.

Abstract

OBJECTIVE

Our purpose was to determine left ventricular size and function in obese pregnant patients during the third trimester.

STUDY DESIGN

Eight morbidly obese pregnant patients had M-mode echocardiography. None were hypertensive or diabetic at the time of study. A group of 36 normal patients were used as controls.

RESULTS

Left ventricular end-diastolic dimension, fractional shortening, and cardiac index were not significantly different between the two groups. Left atrial size, left ventricular wall thickness, interventricular septal thickness, and left ventricular mass were greater in the obese group. The radius-to-wall thickness ratio was significantly smaller in the obese group.

CONCLUSIONS

(1) Left ventricular dimension and function in obese patients was similar to that of nonobese patients. (2) The left ventricle was found to be significantly hypertrophied in obese patients. Left ventricular reconfiguration appears to be important in preserving left ventricular function. Whether these changes are specific to pregnancy or secondary to maternal obesity remains to be determined.

摘要

目的

我们的目的是确定孕晚期肥胖孕妇的左心室大小和功能。

研究设计

8名病态肥胖孕妇接受了M型超声心动图检查。研究时她们均无高血压或糖尿病。选取36名正常孕妇作为对照组。

结果

两组之间左心室舒张末期内径、缩短分数和心脏指数无显著差异。肥胖组的左心房大小、左心室壁厚度、室间隔厚度和左心室质量更大。肥胖组的半径与壁厚度之比显著更小。

结论

(1)肥胖患者的左心室大小和功能与非肥胖患者相似。(2)发现肥胖患者的左心室明显肥厚。左心室重构似乎对维持左心室功能很重要。这些变化是妊娠特有的还是继发于母体肥胖仍有待确定。

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