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Central serotonergic hyperresponsivity in late-onset Alzheimer's disease.

作者信息

McLoughlin D M, Lucey J V, Dinan T G

机构信息

Department of Psychiatry, Trinity College Medical School, St. James's Hospital, London, England.

出版信息

Am J Psychiatry. 1994 Nov;151(11):1701-3. doi: 10.1176/ajp.151.11.1701.

DOI:10.1176/ajp.151.11.1701
PMID:7943465
Abstract

The prolactin response to oral d-fenfluramine (30 mg) was measured in nine patients with late-onset Alzheimer's disease and in an elderly comparison group. The serotonin-mediated prolactin response was significantly greater in the patients with Alzheimer's disease than in the comparison group. This finding suggests that central serotonin responsivity is greater in Alzheimer's disease.

摘要

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