丛状神经鞘瘤

Plexiform schwannoma.

作者信息

Megahed M

机构信息

Department of Dermatology, Heinrich Heine University, Dusseldorf, Germany.

出版信息

Am J Dermatopathol. 1994 Jun;16(3):288-93. doi: 10.1097/00000372-199406000-00011.

DOI:10.1097/00000372-199406000-00011

PMID:7943637

Abstract

We report the clinical, histopathologic, and immunohistopathologic features of two cases of plexiform schwannoma. This rare benign tumor is worthy of recognition because it can be misdiagnosed as plexiform neurofibroma. Differentiation from plexiform neurofibroma is important because the latter is pathognomonic of von Recklinghausen disease and carries a significant risk of malignant transformation. Plexiform schwannoma is, in contrast, not necessarily associated with von Recklinghausen disease and malignant transformation has never been observed.

摘要

我们报告了两例丛状神经鞘瘤的临床、组织病理学和免疫组织病理学特征。这种罕见的良性肿瘤值得引起重视，因为它可能被误诊为丛状神经纤维瘤。与丛状神经纤维瘤进行鉴别很重要，因为后者是冯·雷克林豪森病的特征性表现，且具有显著的恶变风险。相比之下，丛状神经鞘瘤不一定与冯·雷克林豪森病相关，且从未观察到恶变情况。