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[提高急性外源性和内毒素中毒紧急解毒效果的方法]

[Ways of increasing effectiveness of emergency detoxication in acute exo- and endotoxicoses].

作者信息

Luzhnikov E A, Gol'dfarb Iu S, Musselius S G

出版信息

Anesteziol Reanimatol. 1993 Jan-Feb(1):56-65.

PMID:7943867
Abstract

The experience in complex detoxication in acute poisonings and endotoxemias (sepsis, burn-induced toxemia, alcohol and narcotic abstinence, acute hepatorenal failure) has been analysed. The efficacy of various detoxication techniques have been assessed. The techniques compared were sorption dialysis and pharmacological ones, as well as physiohemotherapy as part of magnetic and UV hemotherapy, enhancing the detoxicating process and facilitating adequate correction of homeostasis parameters at all stages of toxemia management. It has been found that hemosorption has the greatest effect on the kinetics of toxic compounds, while physiohemotherapy has the greatest effect on homeostasis parameters. Rational approach to complex detoxication leads to the improvement in treatment results.

摘要

分析了急性中毒和内毒素血症(败血症、烧伤性毒血症、酒精和麻醉品戒断、急性肝肾衰竭)复杂解毒的经验。评估了各种解毒技术的疗效。所比较的技术包括吸附透析和药理学技术,以及作为磁疗和紫外线血液疗法一部分的物理血液疗法,这些疗法可增强解毒过程,并有助于在毒血症管理的各个阶段对体内稳态参数进行适当校正。结果发现,血液吸附对有毒化合物的动力学影响最大,而物理血液疗法对体内稳态参数影响最大。合理的复杂解毒方法可提高治疗效果。

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