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[肝硬化患者肝衰竭及食管胃静脉曲张出血发病机制中的若干因素]

[Several factors in the pathogenesis of hepatic failure in patients with liver cirrhosis and bleeding from esophageal and gastric varicose veins].

作者信息

Bour A V, Manuk'ian G V, Umruzakov I U, Shertsinger A G

出版信息

Anesteziol Reanimatol. 1993 Mar-Apr(2):32-4.

PMID:7943876
Abstract

Bleeding in patients with liver cirrhosis leads to the activation of catabolic processes, accumulation of end products of nitrogen metabolism and pronounced imbalance of blood plasma amino acids. There is a correlation between the changes observed and disorders in neurological status. The authors hold that increased catabolism, pronounced imbalance of blood plasma amino acids and elevated blood ammonia level are the leading factors affecting the onset of hepatic encephalopathy.

摘要

肝硬化患者出血会导致分解代谢过程激活、氮代谢终产物蓄积以及血浆氨基酸明显失衡。所观察到的这些变化与神经状态紊乱之间存在关联。作者认为分解代谢增加、血浆氨基酸明显失衡以及血氨水平升高是影响肝性脑病发病的主要因素。

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