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[曲马多用于儿童的小型外科手术]

[Use of tramal during minor surgical interventions in children].

作者信息

Ostreĭkov I F, Sen'kov V N, Kurilova E S, Bershinskiĭ V P, Pivovarov S A, Babaev B D

出版信息

Anesteziol Reanimatol. 1993 May-Jun(3):28-31.

PMID:7943899
Abstract

Intraoperative analgesia was performed using a combination of tramal at a dose of 2-2.5 mg/kg and transcranial electrical stimulation under halothane-nitrous oxide-oxygen mask anesthesia. The study was performed in 12 apparently healthy boys aged 11-13 operated on for II to III degree varicocele. The efficacy of postoperative analgesia was assessed in 68 children aged 8 to 14 subjected to surgery for inguinal and umbilical hernia, varicocele, cryptorchidism. Parameters of central hemodynamics and cardiopolygraphy have been assessed. Intraoperative use of tramal was accompanied by a prompt recovery of the balance between sympathetic and parasympathetic impacts on the heart and stability of central hemodynamic parameters. Postoperative analgesia with tramal is an effective technique enabling a prompt recovery of pain-induced disturbances in the relations between sympathetic and parasympathetic compartments of the autonomic nervous system. Among the adverse events one can name nausea (25%), repeated vomiting (12%) and allergic reactions (1.4%).

摘要

术中镇痛采用氟烷-氧化亚氮-氧气面罩麻醉下2-2.5毫克/千克剂量的曲马多与经颅电刺激联合使用。该研究在12名年龄为11至13岁、因II至III度精索静脉曲张而接受手术的表面健康男孩中进行。对68名年龄在8至14岁、因腹股沟疝、脐疝、精索静脉曲张、隐睾症而接受手术的儿童的术后镇痛效果进行了评估。评估了中心血流动力学和心电图参数。术中使用曲马多后,交感神经和副交感神经对心脏的影响之间的平衡迅速恢复,中心血流动力学参数也保持稳定。曲马多术后镇痛是一种有效的技术,能使自主神经系统交感和副交感部分之间因疼痛引起的关系紊乱迅速恢复。在不良事件中,可提及恶心(25%)、反复呕吐(12%)和过敏反应(1.4%)。

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