Arakawa M, Miwa H, Noda T, Ito Y, Kagawa K, Nishigaki K, Kambara K, Tomita M, Hirakawa S
Second Department of Internal Medicine, Gifu University School of Medicine, Japan.
Angiology. 1994 Oct;45(10):841-9. doi: 10.1177/000331979404501003.
During ventricular systole, the left atrium (LA) stores a certain amount of ventricular stroke volume; this is defined as an LA storage volume. From cineangiocardiograms, an LA storage fraction is obtained as the ratio of the LA storage volume to left ventricular stroke volume. From the pulmonary vein (PV) flow velocity-time profile, the LA storage fraction may be estimated as a ratio of the PV flow velocity-time integral during systole (Sa) to a sum of that during systole and diastole (Sa+Da), namely, Sa/(Sa+Da), provided that the PV cross-sectional area remains relatively unchanged during one cardiac cycle and that the PV flow velocity-time profile is similar in any of the PVs draining to the LA. To evaluate usefulness of Doppler echocardiographic method of estimating the LA storage fraction, the authors measured the LA storage fraction from the left upper PV flow velocity-time profile by transesophageal Doppler echocardiography and compared it with the LA storage fraction from conventional cineangiocardiographic volumes. Subjects were 23 patients with a variety of cardiac diseases in normal sinus rhythm, ranging from eighteen to seventy-four years of age. The LA storage fraction was 0.58 +/- 0.12 (mean +/- SD) from cineangiocardiography and 0.64 +/- 0.08 from Doppler echocardiography larger than that from cineangiocardiography (P < 0.01), the correlation was good (r = 0.643). The authors conclude that the left upper PV flow velocity-time profile appears to provide a better correlation with that by cineangiography and may be used as a reliable quantitative estimate of the LA storage fraction.
在心室收缩期，左心房（LA）储存一定量的心室搏出量；这被定义为左心房储存量。从心血管造影影片中，左心房储存分数可通过左心房储存量与左心室搏出量的比值获得。从肺静脉（PV）流速-时间曲线来看，假设在一个心动周期中肺静脉横截面积相对不变，且引流至左心房的任何一条肺静脉的流速-时间曲线相似，那么左心房储存分数可通过收缩期肺静脉流速-时间积分（Sa）与收缩期和舒张期积分之和（Sa+Da）的比值来估算，即Sa/(Sa+Da)。为评估多普勒超声心动图法估算左心房储存分数的实用性，作者通过经食管多普勒超声心动图测量左上肺静脉流速-时间曲线的左心房储存分数，并将其与传统心血管造影容积法测得的左心房储存分数进行比较。研究对象为23例窦性心律正常的各种心脏病患者，年龄在18至74岁之间。心血管造影测得的左心房储存分数为0.58±0.12（均值±标准差），多普勒超声心动图测得的为0.64±0.08，高于心血管造影测得的结果（P<0.01），相关性良好（r=0.643）。作者得出结论，左上肺静脉流速-时间曲线与心血管造影法的相关性似乎更好，可作为左心房储存分数的可靠定量评估方法。
