Matsuda Y, Tanimoto Y, Kobayashi Y, Hayashi K, Masuda T, Sakata K
Saiseikai Shimonoseki General Hospital, Yamaguchi, Japan.
Ann Thorac Surg. 1994 Sep;58(3):795-8. doi: 10.1016/0003-4975(94)90751-x.
Left ventricular ejection changes obtained from left ventricle roentgenograms were analyzed before and after coronary artery bypass grafting in 22 consecutive patients with chronic obstructive left anterior descending coronary artery disease receiving collaterals before surgical revascularization. The collateral vessels all disappeared after surgical revascularization. After operation, ejection changes of anterobasal, anterolateral and apical walls supplied by the left anterior descending coronary artery improved from 43.6% +/- 9.7% to 48.5% +/- 8.6% (p < 0.05), from 35.2% +/- 10.9% to 39.4% +/- 9.5% (p < 0.05), and from 46.0% +/- 10.6% to 50.0% +/- 8.7% (p < 0.05), respectively. The improvement in left ventricular wall motion did not appear to be related to the extent of preoperative collateralization. Thus, left ventricular wall motion was impaired in the area supplied by collaterals and was improved by myocardial revascularization. These results suggest that coronary blood flow, even through well-developed collaterals, may not be sufficient, which may produce chronic active ischemia and impaired left ventricular wall motion.
对22例慢性阻塞性左前降支冠状动脉疾病患者在手术血运重建前接受侧支循环供血,连续进行冠状动脉搭桥术前后的左心室X线片所获得的左心室射血变化进行分析。手术血运重建后所有侧支血管均消失。术后,由左前降支冠状动脉供血的前基底壁、前外侧壁和心尖壁的射血变化分别从43.6%±9.7%改善至48.5%±8.6%(p<0.05),从35.2%±10.9%改善至39.4%±9.5%(p<0.05),以及从46.0%±10.6%改善至50.0%±8.7%(p<0.05)。左心室壁运动的改善似乎与术前侧支循环的程度无关。因此,侧支循环供血区域的左心室壁运动受损,而心肌血运重建可使其改善。这些结果表明,即使通过发育良好的侧支循环,冠状动脉血流可能也不足,这可能会产生慢性活动性缺血并损害左心室壁运动。