Volcheck G W, Li J T
Division of Allergic Diseases, Mayo Clinic and Foundation, Rochester, Minn.
Arch Intern Med. 1994 Oct 10;154(19):2243-5.
We measured serial serum tryptase levels in a case of intraoperative anaphylaxis caused by allergy to latex. The serum tryptase level was elevated 7 hours after the hypotensive episode and returned to normal after recovery 4 months later. Both skin tests to latex and serum IgE to latex confirmed latex allergy in this patient. To our knowledge, this is the first report of an elevated serum tryptase level in intraoperative anaphylaxis caused by latex allergy. This observation confirms the role of mast cell degranulation in anaphylaxis caused by allergy to latex.
我们检测了一例因对乳胶过敏导致术中过敏反应患者的系列血清类胰蛋白酶水平。在低血压发作7小时后血清类胰蛋白酶水平升高，4个月后恢复正常。针对乳胶的皮肤试验和血清乳胶IgE均证实该患者对乳胶过敏。据我们所知，这是首例关于乳胶过敏导致术中过敏反应时血清类胰蛋白酶水平升高的报告。这一观察结果证实了肥大细胞脱颗粒在乳胶过敏所致过敏反应中的作用。
