Sclerosing hemangioma of the lung. Granulomatous variant.

We present a case of granulomatous sclerosing hemangioma of the lung in a 43-year-old white woman in whom a pulmonary nodule was found on a routine chest roentgenogram. Surgical resection of a well-circumscribed pulmonary nodule was performed. Histologically, the tumor showed the typical features of sclerosing hemangioma with the unusual feature of a florid granulomatous reaction. Immunohistochemical studies using antibodies for epithelial membrane antigen decorated the tumoral cells, while factor VIII was positive in the vascular structure. Histochemical stains for microorganisms yielded negative results.