Moran C A, Zeren H, Koss M N
Department of Pulmonary and Mediastinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Arch Pathol Lab Med. 1994 Oct;118(10):1028-30.
We present a case of granulomatous sclerosing hemangioma of the lung in a 43-year-old white woman in whom a pulmonary nodule was found on a routine chest roentgenogram. Surgical resection of a well-circumscribed pulmonary nodule was performed. Histologically, the tumor showed the typical features of sclerosing hemangioma with the unusual feature of a florid granulomatous reaction. Immunohistochemical studies using antibodies for epithelial membrane antigen decorated the tumoral cells, while factor VIII was positive in the vascular structure. Histochemical stains for microorganisms yielded negative results.
我们报告一例43岁白人女性的肺部肉芽肿性硬化性血管瘤，该患者在常规胸部X线检查时发现肺部结节。对一个边界清晰的肺结节进行了手术切除。组织学上，肿瘤表现出硬化性血管瘤的典型特征，同时具有显著的肉芽肿反应这一不寻常特征。使用上皮膜抗原抗体进行的免疫组织化学研究显示肿瘤细胞呈阳性，而血管结构中因子VIII呈阳性。微生物的组织化学染色结果为阴性。
