Salvatori S, Biral D, Furlan S, Marin O
CNR, University of Padova, Italy.
Biochem Biophys Res Commun. 1994 Sep 30;203(3):1365-70. doi: 10.1006/bbrc.1994.2335.
We have raised a polyclonal antibody against a synthetic peptide chosen within the deduced sequence of the myotonic dystrophy gene product. This antibody binds to a protein whose molecular weight is in the range of 50-54 kDa in Western blotting of rat, rabbit and human muscles. Biochemical studies seem to indicate that this protein is a peripheral component of sarcoplasmic reticulum as well as of plasma membrane.
我们针对强直性肌营养不良基因产物推导序列中选取的一段合成肽制备了多克隆抗体。在对大鼠、兔子和人类肌肉进行的蛋白质免疫印迹分析中，该抗体可与一种分子量在50 - 54 kDa范围内的蛋白质结合。生化研究似乎表明，这种蛋白质是肌浆网以及质膜的外周成分。
