[Antisense oligonucleotides containing 1-(beta-D-2'-deoxy-threo-pentofuranosyl)thymine at the 3'- and 5'-end].
作者信息
Krynetskaia N F, Chebotar' O A, Ibragim K Kh, Romanova E A, Tashlitskiĭ V N, Oretskaia T S, Sokolova N I, Shabarova Z A
出版信息
Bioorg Khim. 1994 Jun;20(6):669-75.
PMID:7945461
Abstract
Oligonucleotides with 3'- and 5'-terminal 1-(beta-D-2'-deoxy-threo-pentafuranosyl)thymin residues (inversion at C3'-atom) were obtained by the automatic phosphoramidite synthesis. The modifications protect oligonucleotides from the nuclease degradation and do not affect the stability of nucleic acid duplexes.
摘要
Zotero 插件