[桂附地黄丸提取物对兔IgG加速肾毒血清诱导的小鼠肾炎的影响]
[Effects of guifu dihuang pills extract on rabbit IgG accelerated mouse nephritis induced by nephrotoxic serum].
作者信息
Xiong Y L, Wang J H, Zong G Z, Tu G R, Feng Q R, He W, Cai H B, Yu J G, Hui L Q
机构信息
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
出版信息
Zhongguo Zhong Yao Za Zhi. 1994 May;19(5):302-4, inside backcover.
The effects of Guifu Dihuang Pills extract were observed in rabbit IgG accelerated mouse nephritis model induced by nephrotoxic serum. The results showed that this preparation could increase serum albumin, reduce urine protein, serum urea nitrogen and total cholesterol in serum, and improve the histological lesions in kidneys. The effects of Guifu Dihuang Pills extract in dosages of 0.3g/kg and 1.2g/kg were similar to those of cyclophosphamide 0.015g/kg.
在肾毒性血清诱导的兔IgG加速型小鼠肾炎模型中观察了桂附地黄丸提取物的作用。结果显示，该制剂可增加血清白蛋白，减少尿蛋白、血清尿素氮和血清总胆固醇，并改善肾脏的组织学损伤。0.3g/kg和1.2g/kg剂量的桂附地黄丸提取物的作用与0.015g/kg环磷酰胺的作用相似。
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