Gill P, Cyr D, Afrakhtah M, Mack L, Easterling T
Department of Obstetrics and Gynecology, University of Washington, Seattle 98195.
Fetal Diagn Ther. 1994 Jul-Aug;9(4):278-82. doi: 10.1159/000263948.
Advanced pregnancy termination with uterotonic agents with their inherent risk for occurrence of a live birth and surgical evacuation of a fetus perceived to be vigorous can both be sources of emotional anguish for women. They argue for offering women an option for induction of fetal demise prior to uterine evacuation. We report on our experience with 60 pregnancies in which lethal fetal administration of potassium chloride was performed prior to evacuation of the uterus. We describe a double-bolus technique for funic intravascular injection of potassium chloride to arrest the fetal heart. There were no maternal complications and the procedure was successful in 86.7% (n = 52) of the cases; of the remaining 8 cases, 7 had demise induced by direct fetal cardiac injection, and a live birth occurred in 1 case.
使用宫缩剂进行晚期妊娠终止，因其存在活产风险，以及对看似活跃的胎儿进行手术取出，都可能给女性带来情感痛苦。这促使人们考虑为女性提供在子宫排空之前诱导胎儿死亡的选择。我们报告了60例妊娠的经验，这些妊娠在子宫排空之前进行了氯化钾致死性胎儿给药。我们描述了一种用于脐带血管内注射氯化钾以停止胎儿心脏跳动的双推注技术。没有发生母体并发症，该手术在86.7%（n = 52）的病例中成功；其余8例中，7例通过直接胎儿心脏注射诱导死亡，1例发生活产。
