Turjanmaa K
Department of Dermatology, Tampere University Hospital, Finland.
Ann Med. 1994 Aug;26(4):297-300. doi: 10.3109/07853899409147905.
Immediate, IgE-mediated allergy to natural rubber latex has recently been found to be responsible for contact and generalized urticaria, protein contact dermatitis, rhinitis, asthma and even fatal anaphylactic reactions. The proteins present in latex from the rubber tree (Hevea brasiliensis) can still persist in rubber end-products where they are capable of sensitizing exposed users. Atopic people and those with hand eczema are prone to become sensitized by natural rubber latex, which often causes occupational problems in connection with the use of protective gloves. But people blowing up balloons and those using condoms are also at risk if their symptoms are misinterpreted. Severe adverse reactions caused by rubber products in medicare cannot be prevented if the diagnosis has not been made before operations and medical examinations. So the most important task today is to develop reliable and safe methods for diagnosing natural rubber latex allergy and to manufacture rubber products with fewer allergens.
最近发现，对天然橡胶乳胶的速发型、IgE介导的过敏反应会导致接触性和全身性荨麻疹、蛋白质接触性皮炎、鼻炎、哮喘，甚至致命的过敏反应。橡胶树（巴西橡胶树）乳胶中的蛋白质仍会残留在橡胶最终产品中，从而使接触者产生过敏。特应性体质者和手部湿疹患者容易对天然橡胶乳胶过敏，这在使用防护手套时常常引发职业问题。但是，如果症状被误诊，吹气球的人和使用避孕套的人也有风险。如果在手术和医学检查前未做出诊断，就无法预防医疗保健中橡胶制品引起的严重不良反应。因此，当今最重要的任务是开发可靠、安全的天然橡胶乳胶过敏诊断方法，并生产过敏原较少的橡胶制品。
