Mizutari K, Kuriya N, Ono T
Department of Dermatology, Kumamoto University School of Medicine, Japan.
J Dermatol. 1995 Jan;22(1):19-23. doi: 10.1111/j.1346-8138.1995.tb03334.x.
We conducted a questionnaire study of immediate allergy to natural rubber gloves among 2,408 medical workers who had used rubber gloves at Kumamoto University Hospital and allied hospitals. The response rate was 64.5% (1,321 workers). Among them, 8.5% (7.0-10.0% at 95% confidence limit) replied that they had experienced immediate allergy to rubber gloves. There were significant correlations among the frequency of rubber glove use, a history of atopic dermatitis or contact dermatitis, and the presence of skin lesions due to allergic reactions to rubber gloves. In 27 workers, skin lesions were associated with general symptoms. Of 59 workers who experienced immediate allergy and were tested for latex-specific IgE, 4 persons were positive. We conclude that the frequency of contact allergy to natural rubber products is substantially prevalent among Japanese hospital personnel and that education and awareness of this allergy are important.
我们对熊本大学医院及相关医院中2408名使用过橡胶手套的医护人员进行了一项关于天然橡胶手套速发型过敏的问卷调查。回复率为64.5%（1321名工作人员）。其中，8.5%（95%置信区间为7.0 - 10.0%）的人回答他们曾经历过对橡胶手套的速发型过敏。橡胶手套使用频率、特应性皮炎或接触性皮炎病史以及因橡胶手套过敏反应导致的皮肤病变之间存在显著相关性。27名工作人员的皮肤病变伴有全身症状。在59名经历过速发型过敏并接受乳胶特异性IgE检测的工作人员中，4人呈阳性。我们得出结论，日本医院工作人员中对天然橡胶产品接触性过敏的频率相当普遍，对此类过敏的教育和认识很重要。
