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肺切除术后脓胸

Post-pneumonectomy empyema.

作者信息

Wong P S, Goldstraw P

机构信息

Dept. of Thoracic Surgery, Royal Brompton National Heart and Lung Hospital, London, UK.

出版信息

Eur J Cardiothorac Surg. 1994;8(7):345-9; discussion 349-50. doi: 10.1016/1010-7940(94)90027-2.

Abstract

Empyema remains a formidable complication following pneumonectomy, and compounds the mortality of such major surgery. Our experience of 41 cases of post-pneumonectomy empyema (PPE) is presented. There is no universally appropriate treatment and management depends upon the patient's general condition and the presence of associated fistulas. Initial management consists of drainage in all cases. This may be continued if the patient is unfit for further procedures or if there is any doubt about the possibility of an early relapse. Since 1979, we have treated 23 cases of PPE not associated with bronchopleural fistula (BPF) ("simple" PPE). All were treated by rib resection and open drainage. Subsequently in four patients, Portovac drainage eradicated the space and infection within 3 and 12 months. One patient died of pulmonary embolus one day after open drainage. Three patients were unfit for further treatment and one patient refused further treatment. One patient underwent Schede thoracoplasty and had no further infection. Thirteen patients were re-admitted after a period of open tube drainage (3-28 weeks), the infected space was irrigated to sterility and closed. This was successful in eight cases which have remained sterile 9 months to 9 years later. Five patients developed recurrent PPE and three patients have remained sterile following repeated irrigation and closure. The management of PPE is further complicated by concurrent fistulas. Since 1979, 18 patients have had PPE complicated by fistula ("complex" PPE), often recurrent following previous unsuccessful attempts at closure. Treatment has been individualized, and has often required further major surgery. Small BPFs closed with drainage and the space was obliterated with Portovac drainage in three patients.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

脓胸仍是肺切除术后一个严重的并发症,会增加这类大手术的死亡率。本文介绍了我们对41例肺切除术后脓胸(PPE)的治疗经验。目前尚无普遍适用的治疗方法,治疗方案取决于患者的一般状况以及是否存在相关瘘管。所有病例的初始治疗均为引流。如果患者不适合进一步手术,或者对早期复发的可能性存在疑问,则可继续进行引流。自1979年以来,我们共治疗了23例与支气管胸膜瘘(BPF)无关的PPE(“单纯性”PPE)。所有患者均接受了肋骨切除和开放引流术。随后,4例患者通过负压引流在3至12个月内消除了胸腔积液并控制了感染。1例患者在开放引流术后一天死于肺栓塞。3例患者不适合进一步治疗,1例患者拒绝进一步治疗。1例患者接受了Schede胸廓成形术,此后未再发生感染。13例患者在开放引流一段时间(3至28周)后再次入院,对感染的胸腔进行冲洗直至无菌后闭合。8例患者治疗成功,在9个月至9年后仍保持无菌状态。5例患者发生复发性PPE,3例患者在反复冲洗和闭合后保持无菌状态。并发瘘管使PPE的治疗更加复杂。自1979年以来,18例患者的PPE合并瘘管(“复杂性”PPE),在先前的闭合尝试失败后常复发。治疗方案个体化,通常需要进一步的大手术。3例小BPF患者通过引流闭合,并用负压引流消除胸腔积液。

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