Paltiel H J
Department of Radiology, Children's Hospital, Boston, MA 02115.
Semin Ultrasound CT MR. 1994 Aug;15(4):290-305. doi: 10.1016/s0887-2171(05)80088-5.
In the neonate with cholestasis, clinical features and standard tests of liver function frequently cannot distinguish between diseases of the hepatocyte and those of the biliary tree. Therefore, a multidisciplinary approach to diagnosis is required. A priority in investigation is the identification of patients requiring surgery. A correct diagnosis regarding the need for surgery can be made in the majority of cases after synthesis of information obtained from abdominal sonography, hepatobiliary scintigraphy, and liver biopsy. Intraoperative cholangiography is performed routinely to precisely delineate the anatomy of the intrahepatic and extrahepatic bile ducts.
对于患有胆汁淤积的新生儿，临床特征和肝功能的标准检查常常无法区分肝细胞疾病和胆管树疾病。因此，需要采用多学科方法进行诊断。调查的一个重点是识别需要手术的患者。在综合腹部超声、肝胆闪烁显像和肝活检所获得的信息后，大多数情况下可以对是否需要手术做出正确诊断。术中常规进行胆管造影，以精确描绘肝内和肝外胆管的解剖结构。
