Vaishnav S, Aziz S, Layton C
Cardiac Department, London Chest Hospital.
Br Heart J. 1994 Sep;72(3):288-93. doi: 10.1136/hrt.72.3.288.
To evaluate the results of implantation of Wiktor tantalum wire coronary stents in stenosed or occluded coronary vessels or in saphenous vein bypass grafts.
A retrospective analysis of clinical and angiographic data from patients treated with tantalum wire stents implanted by one operator at two centres.
52 patients undergoing conventional balloon angioplasty had 67 lesions treated by stents after acute or threatened closure of the target vessel, or because the lesions concerned were considered to be at particularly high risk of becoming restenosed, or because the result of primary angioplasty was inadequate.
65 of the 67 lesions were successfully stented although in two cases the first attempt failed and a second stent was then implanted successfully. There were no cases of stent occlusion and no myocardial infarctions in hospital or in the follow up period of 1-20 months. Eight patients had haemorrhagic complications that were minor in 4. One patient later had coronary bypass surgery after failure to stent a lesion. Angiographic follow up at a mean of 6 months after stenting showed restenosis associated with 4 of 47 stents studied. All patients with chest pain had had repeat angiography, and 84% of those without symptoms also agreed to reinvestigation after about 6 months.
The Wiktor tantalum wire stent is an effective means of treating acute complications during angioplasty and seems to offer hope of a significant reduction in the rate of late restenosis in both native coronary vessels and saphenous vein bypass grafts. A prospective comparison of balloon angioplasty and stenting is needed.
评估维克托钽丝冠状动脉支架植入狭窄或闭塞冠状动脉血管或隐静脉旁路移植血管的效果。
对由一名操作者在两个中心植入钽丝支架治疗的患者的临床和血管造影数据进行回顾性分析。
52例行传统球囊血管成形术的患者,因靶血管急性闭塞或有闭塞风险、或因相关病变被认为有特别高的再狭窄风险、或因初次血管成形术效果不佳,共有67处病变接受了支架治疗。
67处病变中的65处成功植入支架,尽管有2例首次尝试失败,随后成功植入了第二个支架。住院期间及1至20个月的随访期内无支架闭塞病例及心肌梗死发生。8例患者出现出血并发症,其中4例为轻微并发症。1例患者在一处病变支架植入失败后接受了冠状动脉搭桥手术。支架植入后平均6个月的血管造影随访显示,在所研究的47个支架中有4个出现再狭窄。所有胸痛患者均接受了重复血管造影,84%无症状患者也同意在约6个月后再次检查。
维克托钽丝支架是治疗血管成形术急性并发症的有效手段,似乎有望显著降低天然冠状动脉血管和隐静脉旁路移植血管的晚期再狭窄率。需要对球囊血管成形术和支架植入术进行前瞻性比较。