Friedman D, Vaughan H G, Erlenmeyer-Kimling L
Electroencephalogr Clin Neurophysiol. 1978 Sep;45(3):319-30. doi: 10.1016/0013-4694(78)90184-0.
Visual event-related potentials (ERP) were recorded from 6 subjects aged 10--15 in response to target stimuli in 2 vigilance tasks which differed in their processing requirements. Stimulus- and response-synchronized averages were computed for each subject for each quartile (Q) of that subject's reaction time (RT) distribution. Late positive complexes (LPC) of identical morphology were seen in the brain potentials from each task. In Q1, the LPC was an undifferentiated, large amplitude, positive-going potential with a parietal-maximum topography. As RT increased, the LPC became increasingly differentiated so that by Q3 3 components in the latency range of P300 were visible: two constant-latency peaks, P286 (fronto-central), P341 (parietal); and one variable-latency deflection, P539 (parietal), whose peak latency lengthened as RT increased. An additional constant-latency peak, P198, was also recorded. Principal component analyses of the averaged wave forms confirmed the visual identification of these components. The fixed-latency peaks identified in the brain potentials of these subjects were similar in timing and topography to previously reported late positive components. This study demonstrated. however, that the LPC can be segregated into stimulus-related and response-related components.
对6名年龄在10至15岁的受试者进行视觉事件相关电位（ERP）记录，以响应两种警觉任务中的目标刺激，这两种任务在处理要求上有所不同。针对每个受试者反应时间（RT）分布的每个四分位数（Q），计算刺激同步和反应同步平均值。在每个任务的脑电中都观察到形态相同的晚期正复合波（LPC）。在Q1中，LPC是一个未分化的、大振幅的正向电位，顶叶为最大波幅部位。随着反应时间增加，LPC变得越来越分化，到Q3时，在P300潜伏期范围内可见3个成分：两个潜伏期恒定的峰，P286（额中央）、P341（顶叶）；以及一个潜伏期可变的偏转波，P539（顶叶），其峰潜伏期随着反应时间增加而延长。还记录到一个额外的潜伏期恒定峰P198。对平均波形进行主成分分析证实了对这些成分的视觉识别。这些受试者脑电中识别出的固定潜伏期峰在时间和波幅部位上与先前报道的晚期正成分相似。然而，本研究表明，LPC可分为与刺激相关和与反应相关的成分。
