氟达拉滨治疗后的神经疾病
Neurological illness following treatment with fludarabine.
作者信息
Johnson P W, Fearnley J, Domizio P, Goldin J, Nagendran K, Gawler J, Rohatiner A Z, Lister T A
机构信息
Department of Medical Oncology, St Bartholomew's Hospital, London, UK.
出版信息
Br J Cancer. 1994 Nov;70(5):966-8. doi: 10.1038/bjc.1994.430.
Abstract
Fludarabine is a comparatively new drug for the treatment of low-grade lymphoid malignancy. This report describes five cases of unusual neurological illnesses occurring after treatment with fludarabine. These suggest that caution should be exercised in patients receiving fludarabine who develop neurological abnormalities, with prompt investigation and if necessary cessation of the drug.
摘要
氟达拉滨是一种用于治疗低度恶性淋巴瘤的相对较新的药物。本报告描述了5例在接受氟达拉滨治疗后出现异常神经系统疾病的病例。这些病例提示，对于接受氟达拉滨治疗且出现神经功能异常的患者应谨慎处理，需及时进行检查，必要时停用该药物。
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