• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Yeast homologue of mammalian Ran binding protein 1.

作者信息

Butler G, Wolfe K H

机构信息

Department of Biochemistry, University College Dublin, Belfield, Ireland.

出版信息

Biochim Biophys Acta. 1994 Nov 22;1219(3):711-2. doi: 10.1016/0167-4781(94)90233-x.

DOI:10.1016/0167-4781(94)90233-x
PMID:7948031
Abstract

A Saccharomyces cerevisiae gene (HTN1) that encodes a homologue of mouse Ran binding protein 1 (RanBP1, also known as HTF9A) was identified, cloned and sequenced. The two proteins are 51% identical in sequence. The HTN1 protein may interact with yeast GSP1, GSP2, and PRP20 proteins in an intracellular signalling pathway equivalent to the mammalian RanBP1-Ran/TC4-RCC1 pathway. RanBP1 homologues also exist in worms and rice.

摘要

相似文献

1
Yeast homologue of mammalian Ran binding protein 1.
Biochim Biophys Acta. 1994 Nov 22;1219(3):711-2. doi: 10.1016/0167-4781(94)90233-x.
2
RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4.RanBP1是一种与Ran/TC4结合的类Ras核G蛋白，它通过Ran/TC4抑制RCC1。
Mol Gen Genet. 1995 Jun 25;247(6):661-9. doi: 10.1007/BF00290397.
3
RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae.RNA1编码一种对Gsp1p具有特异性的GTP酶激活蛋白，Gsp1p是酿酒酵母的Ran/TC4同源物。
J Biol Chem. 1995 May 19;270(20):11860-5. doi: 10.1074/jbc.270.20.11860.
4
GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.GSP1和GSP2，酿酒酵母中prp20-1突变体的遗传抑制因子：参与维持细胞核组织的GTP结合蛋白。
Mol Cell Biol. 1993 Apr;13(4):2152-61. doi: 10.1128/mcb.13.4.2152-2161.1993.
5
Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast.Ran结合蛋白-1是芽殖酵母中Ran/RCC1分子开关系统的重要组成部分。
J Biol Chem. 1995 Feb 3;270(5):1975-8. doi: 10.1074/jbc.270.5.1975.
6
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.酵母Ran/TC4同源物的GTP结合形式会阻断核蛋白的输入以及细胞质中聚腺苷酸（poly(A)+）RNA的出现。
Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):225-9. doi: 10.1073/pnas.92.1.225.
7
A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue.一种核蛋白输入所需的蛋白质Mog1p，直接与酿酒酵母的Ras同系物GTP-Gsp1p相互作用。
Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15388-93. doi: 10.1073/pnas.95.26.15388.
8
Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein.Yrb2p是一种与Nup2p相关的酵母蛋白，它与酵母Ran-GTPase激活蛋白Rna1p存在功能重叠。
Mol Cell Biol. 1997 Apr;17(4):2235-46. doi: 10.1128/MCB.17.4.2235.
9
Site-directed mutagenesis of the yeast PRP20/SRM1 gene reveals distinct activity domains in the protein product.酵母PRP20/SRM1基因的定点诱变揭示了该蛋白质产物中不同的活性结构域。
Mol Gen Genet. 1994 Oct 17;245(1):32-44. doi: 10.1007/BF00279748.
10
The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1.细胞核内的RAN/TC4 GTP酶的C末端可稳定结合GDP的状态，并介导与RCC1、RAN-GAP和HTF9A/RANBP1的相互作用。
J Biol Chem. 1995 Jun 16;270(24):14405-11. doi: 10.1074/jbc.270.24.14405.

引用本文的文献

1
Amino acid-dependent Gcn4p stability regulation occurs exclusively in the yeast nucleus.氨基酸依赖性的Gcn4p稳定性调节仅在酵母细胞核中发生。
Eukaryot Cell. 2002 Oct;1(5):663-72. doi: 10.1128/EC.1.5.663-672.2002.
2
Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway.酵母Ran结合蛋白1（Yrb1）在细胞核和细胞质之间穿梭，并通过依赖CRM1（XPO1）的途径从细胞核输出。
Mol Cell Biol. 2000 Jun;20(12):4295-308. doi: 10.1128/MCB.20.12.4295-4308.2000.
3
A T42A Ran mutation: differential interactions with effectors and regulators, and defect in nuclear protein import.
一种T42A Ran突变：与效应物和调节因子的差异相互作用以及核蛋白导入缺陷。
Mol Biol Cell. 1997 Dec;8(12):2591-604. doi: 10.1091/mbc.8.12.2591.
4
Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.核转运缺陷和核膜改变与酿酒酵母NPL4基因的突变有关。
Mol Biol Cell. 1996 Nov;7(11):1835-55. doi: 10.1091/mbc.7.11.1835.
5
Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex.酵母N1e3p/Nup170p对于核孔复合体内FG核孔蛋白的正常化学计量是必需的。
Mol Cell Biol. 1996 May;16(5):2025-36. doi: 10.1128/MCB.16.5.2025.