Larsson J, Akerlind I, Permerth J, Hörnqvist J O
Department of Surgery, Faculty of Health Sciences, University Hospital, Linköping, Sweden.
Eur J Surg. 1994 Jun-Jul;160(6-7):329-34.
To explore the relationship between nutritional status and quality of life in a group of patients in a surgical department.
Prospective open study.
Department of Surgery, University Hospital, Linköping, Sweden.
The patients (n = 199) included 89 females and 110 males, mean age 59 years.
The nutritional status was assessed by the percentage weight loss (% WL), weight index (WI), arm muscle circumference (AMC), triceps skin fold thickness (TSF), serum-albumin (Alb) and serum-prealbumin (p-Alb) concentration. Malnutrition was classified as three or more abnormal values and the overall frequency was 35%. The quality of life was assessed by a self-administered rating form with a life-domain rating part and a well-being rating part. In the current statistical analysis, the nutritional status and its different nutritional markers were tested for significant associations with the life-domain ratings (n = 7) and wellbeing scales (n = 11).
There were significant relations between malnutrition according to nutritional assessment (p < 0.001), % WL (p < 0.005-0.001), Alb (p < 0.05-0.001), p-Alb (p < 0.01-0.001) and quality of life in all life domains except for the social network sphere. The anthropometric variables AMC and TSF showed no association with life domain ratings. As to the wellbeing ratings, an even stronger and more consistent relation were seen between a malnourished state (p < 0.01-0.001), % WL (p < 0.01-0.001), WI (p < 0.01-0.001), Alb (p < 0.01-0.001) and p-Alb (p < 0.05-0.001). AMC and TSF were not linked to the wellbeing ratings.
In summary, there was a close association between malnutrition and impaired quality of life.
探讨外科一组患者的营养状况与生活质量之间的关系。
前瞻性开放研究。
瑞典林雪平大学医院外科。
患者（n = 199），其中女性89例，男性110例，平均年龄59岁。
通过体重减轻百分比（%WL）、体重指数（WI）、上臂肌肉周长（AMC）、三头肌皮褶厚度（TSF）、血清白蛋白（Alb）和血清前白蛋白（p-Alb）浓度评估营养状况。营养不良定义为三项或更多异常值，总体发生率为35%。生活质量通过一份自我评定量表进行评估，该量表包括生活领域评定部分和幸福感评定部分。在当前的统计分析中，对营养状况及其不同的营养指标与生活领域评定（n = 7）和幸福感量表（n = 11）进行了显著相关性检验。
根据营养评估得出的营养不良（p < 0.001）、%WL（p < 0.005 - 0.001）、Alb（p < 0.05 - 0.001）、p-Alb（p < 0.01 - 0.001）与除社交网络领域外的所有生活领域的生活质量之间存在显著关系。人体测量变量AMC和TSF与生活领域评定无关联。至于幸福感评定，在营养不良状态（p < 0.01 - 0.001）、%WL（p < 0.01 - 0.001）、WI（p < 0.01 - 0.001）、Alb（p < 0.01 - 0.001）和p-Alb（p < 0.05 - 0.001）之间观察到更强且更一致的关系。AMC和TSF与幸福感评定无关。
总之，营养不良与生活质量受损之间存在密切关联。
