灌注速率和葡萄糖浓度对绵羊肠道Thiry-Vella肠袢葡萄糖吸收的影响。
Effects of perfusion rate and glucose concentration on glucose absorption in intestinal thiry-vella loop in sheep.
作者信息
Hyun H S, Onaga T, Mineo H, Kato S
机构信息
Department of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
出版信息
J Vet Med Sci. 1994 Jun;56(3):617-8. doi: 10.1292/jvms.56.617.
The effects of the perfusion rate and glucose concentration in perfusate on glucose absorption in the intestinal Thiry-Vella loop of conscious sheep were studied. When 10 mM glucose was perfused at the rates of 0.5, 1, 2 and 4 ml/min, the absorption rates were 77.1 +/- 2.2, 54.9 +/- 2.3, 31.6 +/- 2.1 and 12.9 +/- 0.3%, respectively. When 5, 10, 20 and 40 mM glucose solutions were perfused at 1 ml/min, the absorption rates were 75.5 +/- 1.7, 52.2 +/- 2.2, 29.4 +/- 1.9 and 19.5 +/- 0.1%, respectively. We conclude that the perfusion of 10 mM glucose solution at 1 ml/min, in which about a 50% absorption rate was obtained, are the optimal conditions for the study of glucose absorption in the intestinal loop of sheep.
研究了灌流速率和灌流液中葡萄糖浓度对清醒绵羊肠道Thiry-Vella袢葡萄糖吸收的影响。当以0.5、1、2和4 ml/min的速率灌流10 mM葡萄糖时，吸收率分别为77.1±2.2%、54.9±2.3%、31.6±2.1%和12.9±0.3%。当以1 ml/min的速率灌流5、10、20和40 mM葡萄糖溶液时，吸收率分别为75.5±1.7%、52.2±2.2%、29.4±1.9%和19.5±0.1%。我们得出结论，以1 ml/min的速率灌流10 mM葡萄糖溶液（吸收率约为50%）是研究绵羊肠袢葡萄糖吸收的最佳条件。
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