Wall N A, Hogan B L
Department of Cell Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37209.
Curr Opin Genet Dev. 1994 Aug;4(4):517-22. doi: 10.1016/0959-437x(94)90066-c.
Embryonic induction is the process by which signals from one cell population change the developmental fate of another. Polypeptides related to growth factors are one group of molecules mediating many inductive events. Recent data on the embryonic expression and function of signaling proteins related to transforming growth factor beta, in both vertebrate and invertebrate systems, have shown that these molecules play important roles in both pattern formation and tissue specification during embryogenesis.
胚胎诱导是指一个细胞群体发出的信号改变另一个细胞群体发育命运的过程。与生长因子相关的多肽是介导许多诱导事件的一类分子。最近关于脊椎动物和无脊椎动物系统中与转化生长因子β相关的信号蛋白的胚胎表达和功能的数据表明,这些分子在胚胎发生过程中的模式形成和组织特化中都发挥着重要作用。