Klaassen-Broekema N, Van Bijsterveld O P
Utrecht State University, Department of Ophthalmology, The Netherlands.
Eur J Ophthalmol. 1994 Apr-Jun;4(2):126-9. doi: 10.1177/112067219400400210.
This clinical study reports on an unusual start of a band-shaped keratopathy in a patient with diabetic nephropathy on dialytic treatment. The earliest corneal manifestations were centrally located small greyish-white disc-shaped lesions evenly distributed in the interpalpebral area in the left eye. Later a typical peripheral band-shaped keratopathy developed. In the course of the observation period the peripheral keratopathy rapidly spread towards the centre, finally resulting in a complete band-shaped keratopathy in which only the most central original disc-shaped lesions could be identified. Serum calcium and phosphorus concentrations were markedly elevated at the time of the progression of the band-shaped keratopathy but no tertiary hyperparathyroidism was present.
本临床研究报告了一名接受透析治疗的糖尿病肾病患者带状角膜病变的不寻常起始情况。最早的角膜表现为左眼睑裂区内中央部位有小的灰白色盘状病变,分布均匀。随后发展为典型的周边带状角膜病变。在观察期内,周边角膜病变迅速向中央蔓延,最终形成完全性带状角膜病变,仅能识别出最中央的原始盘状病变。带状角膜病变进展时血清钙和磷浓度显著升高,但不存在三发性甲状旁腺功能亢进。