Finger I, Heller C, von Allmen C
Differentiation. 1978 Jul 24;11(1):51-7. doi: 10.1111/j.1432-0436.1978.tb00969.x.
Paramecia may induce in other paramecia specific changes in the expression of genes determining surface protein synthesis, probably via cell-to-cell contact. Transformation from one antigenic type to a newly induced one is stimulated by the pretreatment of a cell with 5-fluorouracil. These observations are considered in terms of the regulation of the activity of genes in stable cells and in unstable cells which tend to transform spontaneously.
草履虫可能通过细胞间接触，诱导其他草履虫在决定表面蛋白合成的基因表达上产生特定变化。用5-氟尿嘧啶预处理细胞可刺激其从一种抗原类型转变为新诱导的抗原类型。这些观察结果是从稳定细胞和倾向于自发转变的不稳定细胞中基因活性的调节方面来考虑的。
