Querleu D, Parmentier D, Chevallier L
Clinique universitaire de gynécologie-obstétrique, Roubaix.
Contracept Fertil Sex. 1993 Feb;21(2):167-72.
The management of an adnexal masses involves several steps: establish the diagnosis of organic ovarian cyst, avoiding a useless and iatrogenic surgery of a functional cyst, knowing that functional cysts may persist more than 3 months and may occur even on low-dose oral contraceptives; cure painful cysts, by ultrasound guided aspiration of some functional cysts or laparoscopic detorsion of twisted adnexae; exclude malignancy, with the help of ultrasound, Doppler and Ca-125 preoperatively, then laparoscopic examination and pathology; failed diagnosis of cancer becomes rare (1 out of 300 laparoscopic surgeries for ovarian cyst); the association of a benign ultrasound and Doppler pattern and of a Ca-125 lower than 35 mUI/ml is almost pathognomonic of a benign cyst; cure benign ovarian cysts with a minimum of surgical trauma; in our series, 84.4% of ovarian cysts are managed laparoscopically, 11.1% by elective laparotomy, 4.5% by laparotomy after an attempt at laparoscopic surgery (that implies that the patient must be informed of the risk of laparotomy); adapt the surgical technique to the pathologic type and size of the cyst, with a high rate of laparotomy in large dermoid cysts, and a high rate of (salpingo-)oophorectomy in peri or postmenopausal cysts; ensure an adequate therapy of early ovarian carcinomas, avoiding understadification and undertreatment; prevent ovarian cancer by a careful long-term follow-up of patients with benign ovarian cysts and by the use of bilateral oophorectomy in postmenopausal patients.
明确诊断为器质性卵巢囊肿,避免对功能性囊肿进行不必要的医源性手术,要知道功能性囊肿可能持续超过3个月,甚至在服用低剂量口服避孕药时也可能发生;通过超声引导抽吸某些功能性囊肿或对扭转的附件进行腹腔镜复位来治疗疼痛性囊肿;借助超声、多普勒和术前的癌抗原125(Ca-125)排除恶性肿瘤,然后进行腹腔镜检查和病理检查;癌症误诊变得罕见(每300例卵巢囊肿腹腔镜手术中有1例);良性超声和多普勒表现以及Ca-125低于35 mUI/ml几乎可确诊为良性囊肿;以最小的手术创伤治疗良性卵巢囊肿;在我们的系列研究中,84.4%的卵巢囊肿通过腹腔镜手术处理,11.1%通过择期剖腹手术,4.5%在尝试腹腔镜手术后进行剖腹手术(这意味着必须告知患者剖腹手术的风险);根据囊肿的病理类型和大小调整手术技术,大的皮样囊肿剖腹手术率高,围绝经期或绝经后囊肿(输卵管)卵巢切除术率高;确保对早期卵巢癌进行充分治疗,避免分期不足和治疗不足;通过对良性卵巢囊肿患者进行仔细的长期随访以及对绝经后患者进行双侧卵巢切除术来预防卵巢癌。