Ryan W G, Roddam R F, Grizzle W E
Department of Psychiatry, University of Alabama School of Medicine, Birmingham.
Ann Clin Psychiatry. 1994 Mar;6(1):7-12. doi: 10.3109/10401239409148832.
Thyroid function tests (T4, T3RU, free thyroxine index) were performed upon admission in 269 acute psychiatric patients during a 2-year period. Thyroid disease was detected in 3% and euthyroid abnormalities in 9.3%. T4 and free thyroxine index were significantly lower in depressed patients than those with mania or schizophrenia. The rate of abnormal thyroid tests was lower in this study than in previously reported surveys of psychiatric admissions. Laboratory techniques or differences in population may be responsible for the difference. The differences in thyroid function test values between psychiatric diagnoses are relatively new findings, and appear worthy of investigation.
在两年时间里,对269名急性精神病患者入院时进行了甲状腺功能测试(T4、T3RU、游离甲状腺素指数)。发现3%的患者患有甲状腺疾病,9.3%的患者甲状腺功能正常但存在异常。抑郁症患者的T4和游离甲状腺素指数显著低于躁狂症或精神分裂症患者。本研究中甲状腺测试异常的发生率低于先前报道的精神病入院调查结果。实验室技术或人群差异可能是造成这种差异的原因。精神科诊断之间甲状腺功能测试值的差异是相对较新的发现,似乎值得研究。