Kostiukevich S V
Morfologiia. 1993 Jul-Aug;105(7-8):144-50.
The method of light microscopy was used for studying the histotopography of endocrinocytes of the vermiform process mucosa of man. The direction of their distribution was found in distal, medial and proximal parts of the vermiform process mucosa. The greatest amount of endocrinocytes in normal conditions per 1 mm2 of the mucous membrane was found in the proximal part and it was getting less towards the distal one. In inflammation there occurs an increase of the amount of endocrinocytes (in acute ordinary appendicitis, it is 1.5 times higher, in the phlegmonous form--2 times). With the development of deep destructive processes in the mucous membrane the content of endocrinocytes is sharply decreased.