衰老与大脑。
Aging and the brain.
作者信息
Goldman J E, Calingasan N Y, Gibson G E
机构信息
Department of Pathology, Columbia University College of Physicians and Surgeons, New York, NY 10032.
出版信息
Curr Opin Neurol. 1994 Aug;7(4):287-93. doi: 10.1097/00019052-199408000-00002.
Abstract
This review considers some of the changes that occur during aging in the mammalian central nervous system. We focus particularly on neurotransmitter systems, calcium homeostasis, synaptic transmission, oxidative metabolism, amyloid deposition, and other neuropathological and anatomical features. Changes during aging in both humans and nonhuman mammals are discussed.
摘要
本综述探讨了哺乳动物中枢神经系统在衰老过程中发生的一些变化。我们特别关注神经递质系统、钙稳态、突触传递、氧化代谢、淀粉样蛋白沉积以及其他神经病理学和解剖学特征。文中讨论了人类和非人类哺乳动物在衰老过程中的变化。
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