Miroshnikov V M, Erman A M
Klin Lab Diagn. 1994(4):15-7.
Blood serum levels of stage-specific antigens were measured by radioimmunoassay and immunodiffusion methods in patients with acute pyelonephritis at various stages of traditional antibacterial therapy and ultraviolet autoblood irradiation. Under study were ferritin, beta 2-microglobulin, C-reactive protein, transferrin, alpha 2-macroglobulin, and haptoglobin levels. Kinetics of the measured proteins was demonstrated and the possibility of applying their identification to assessment of treatment efficacy shown. The levels of these proteins are shown to be not only indicators of inflammation and destruction in pyelonephritis, but to reflect as well the repair reactions in the body which course most actively when UV irradiation of autoblood is added to multiple-modality treatment schemes.
采用放射免疫测定法和免疫扩散法，对急性肾盂肾炎患者在传统抗菌治疗和紫外线自血照射不同阶段的血清阶段特异性抗原水平进行了测定。研究对象包括铁蛋白、β2-微球蛋白、C反应蛋白、转铁蛋白、α2-巨球蛋白和触珠蛋白水平。展示了所测蛋白质的动力学，并表明了将其鉴定结果应用于评估治疗效果的可能性。结果表明，这些蛋白质的水平不仅是肾盂肾炎炎症和破坏的指标，还反映了机体的修复反应，在多模式治疗方案中加入自血紫外线照射时，机体的修复反应最为活跃。
