Falk S J
Bristol Oncology Centre, UK.
Br J Surg. 1994 Sep;81(9):1277-81. doi: 10.1002/bjs.1800810906.
The role of radiotherapy in the management of the axilla in early breast cancer is examined. A few, carefully selected, clinically node-negative postmenopausal women may require no intervention to the axilla. Otherwise, surgical clearance is the preferred sole management of the axilla, resulting in an excellent level of local control and providing optimal information for the use of systemic adjuvant therapy. Axillary radiotherapy can also provide equivalent levels of long-term control in the clinically node-negative axilla, but the chronic disabling syndrome of brachial plexopathy is documented at all radiation doses that can sterilize microscopic disease, irrespective of the radiotherapy technique. A combination of radiotherapy and axillary surgery results in an increased morbidity rate compared with either alone. Women who receive radiotherapy to the breast alone are not at risk of brachial plexopathy.
研究了放射治疗在早期乳腺癌腋窝处理中的作用。少数经过仔细挑选的临床腋窝淋巴结阴性的绝经后女性可能无需对腋窝进行干预。否则，手术清扫是腋窝首选的唯一处理方式，可实现良好的局部控制水平，并为全身辅助治疗的使用提供最佳信息。腋窝放疗在临床腋窝淋巴结阴性的情况下也能提供同等水平的长期控制，但在所有能消灭微小病灶的放射剂量下，无论采用何种放疗技术，都有臂丛神经病变这一慢性致残综合征的记录。与单独采用放疗或手术相比，放疗与腋窝手术联合应用会导致发病率增加。仅接受乳腺放疗的女性不存在臂丛神经病变的风险。
