Stringer M D, Heaton N D, Karani J, Olliff S, Howard E R
Department of Surgery, King's College Hospital, London, UK.
Br J Surg. 1994 Sep;81(9):1328-31. doi: 10.1002/bjs.1800810923.
Clinical and angiographic findings in 53 patients with portal vein occlusion were reviewed to determine the relationship between the pattern of venous occlusion and its aetiology. Five major patterns were identified. Group 1 comprised three children with idiopathic intrahepatic portal vein occlusion alone (hepatoportal sclerosis). Those in group 2 (25 patients), with occlusion of the main portal vein, accounted for almost half the total number and for most of those with a probable congenital aetiology. The ten patients in group 3 had angiographic occlusion and collateralization of the main portal and superior mesenteric veins. Intra-abdominal sepsis, other than that from pancreatic disease, was associated with this pattern of venous occlusion in which the splenic vein is spared. No patients with isolated portal and splenic vein occlusion (group 4) were recorded. Widespread thrombosis throughout the portal venous system (group 5; 15 patients) had a multifactorial aetiology but was typically observed in hypercoagulable states that were also associated with hepatic vein occlusion or other deep vein thromboses.
回顾了53例门静脉闭塞患者的临床和血管造影结果，以确定静脉闭塞模式与其病因之间的关系。确定了五种主要模式。第1组包括三名仅患有特发性肝内门静脉闭塞（肝门静脉硬化）的儿童。第2组（25例患者）为门静脉主干闭塞，几乎占总数的一半，且大多数可能病因是先天性的。第3组的10例患者血管造影显示门静脉主干和肠系膜上静脉闭塞并形成侧支循环。除胰腺疾病引起的腹腔内感染外，腹腔内其他感染与这种脾静脉未受累的静脉闭塞模式相关。未记录到孤立的门静脉和脾静脉闭塞患者（第4组）。门静脉系统广泛血栓形成（第5组；15例患者）病因多因素，但通常在高凝状态下观察到，这种状态也与肝静脉闭塞或其他深静脉血栓形成有关。
